Investigating heart failure mechanics using personalised human biophysical models
نویسندگان
چکیده
Background Heart failure (HF) is a pathological condition during which the pump function of the heart is compromised. There are two major forms: diastolic and systolic HF. Whilst the majority of patients exhibit systolic HF (reduced ejection fraction), diastolic HF (normal ejection fraction) has also been found in almost half of HF patients. A major question in this field is the inter-relationship between diastolic and systolic HF. The mechanisms underlying both pathologies are still poorly understood.
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